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一种可以防御不同亚型流感病毒的通用疫苗已接近成为现实！

行业动态 2015-12-10 浏览：4096次

一种可以防御不同亚型流感病毒的通用疫苗已接近成为现实。美国国立卫生研究院的研究人员已经从H1N1流感病毒中开发出一种具有稳定血凝素（HA）刺突的纳米疫苗（1）。这种H1 HA刺突免疫原可诱发小鼠和雪貂体内的抗体交叉反应，从而避免因不同HA亚型感染（H5）导致的疾病发生。虽然该疫苗未引起广泛的病毒中和反应，但其保护机制经证实为抗体介导型。这些令人振奋的结果显示，该种仅含血凝素（HA）刺突的纳米疫苗可刺激潜在广泛的免疫反应，以抵御不同的流感病毒株。

中国投入流感病毒研究逐年上升，北京更是全球发表最多文献的城市。 GeneTex在流感抗体的开发不遗余力，为您准备一系列的优质抗体，请点击这里访问我们的网站，寻找您需要的抗体。您科研的好伙伴GeneTex。

Selected Antibodies for Influenza Virus

GeneTex has supported the world's leading researchers for over 15 years with our quality antibodies. Our products continue to be referenced in leading publications and we are proud to be able to contribute to the research community. In this GeneTex newsletter issue, we would like to highlight our catalog of Influenza virus antibodies.

There are three types of influenza virus: Types A, B, and C. The influenza A and B viruses are the ones most associated with serious human infections, while the Type C cases are clinically much milder. The main antigenic determinants of influenza A and B viruses are the hemagglutinin (HA) and neuraminidase (NA) transmembrane glycoproteins. Based on the antigenicity of these glycoproteins, influenza A viruses are further subdivided into sixteen "H" (H1-H16) and nine "N" (N1-N9) subtypes. The influenza A virus genome consists of eight separate RNA segments that encode the proteins (i.e., PB1, PB2, PA, HA, NA, NP, M1, M2, NS1, and NS2) essential for host infection, viral genome replication, and virus particle packaging.


FluA H1N1 HA (GTX127295)	FluA H5N3 HA (GTX127299)	FluA H7N7 HA (GTX127303)	FluA H9N2 HA (GTX127305)
WB analysis on MDCK cell lysates infected with different subtypes of human and avian influenza virus A by using influenza A Virus H1N1 HA antibody (GTX127295), influenza A Virus H5N3 HA antibody (GTX127299), influenza A virus H7N7 HA antibody (GTX127303), and influenza A virus H9N2 HA antibody (GTX127305).

Click here to view the full list of antibodies against Influenza virus proteins.

Product Highlight - Influenza A


Influenza A Virus NS1 antibody (GTX125990)		Influenza A Virus NP antibody (GTX125989)
ICC/IF analysis with Influenza A Virus NS1 antibody on Vero cells infected with influenza A virus (WSN).		ICC/IF analysis with Influenza A Virus NP antibody on Vero cells infected with influenza A virus (WSN).


Influenza A Virus H1N1 Hemagglutinin (HA) antibody [GT223] (GTX629750)		Influenza A Virus NP antibody [GT1236] (GTX629633)
ICC/IF analysis with Influenza A Virus H1N1 HA (FluA HA) antibody on DF1 cells infected with influenza A virus (WSN).		ICC/ IF analysis with influenza A Virus NP antibody on DF1 cells infected with influenza A virus (WSN).


Influenza A Virus M1 antibody (GTX125928)	Influenza A Virus M2 antibody (GTX125951)	Influenza A Virus NP antibody [GT1236] (GTX629633)	Influenza A Virus NS1 antibody (GTX125990)
WB analysis with Influenza A Virus M1 antibody on DF-1 cell lysate. (A) Mock control. (B) influena A virus (WSN) infection.	WB analysis with Influenza A Virus M2 antibody on DF-1 cell lysate. (A) Mock control. (B) influena A virus (WSN) infection.	WB analysis with Influenza A Virus NP antibody on DF-1 cell lysate. (A) Mock control. (B) influena A virus (WSN) infection.	WB analysis with Influenza A Virus NS1 antibody on DF-1 cell lysate. (A) Mock control. (B) influena A virus (WSN) infection.

Cat. No.	Product Name	Host & Clonality	Application
GTX125951	Influenza A virus M2 (matrix protein)	Rb pAb	ICC/IF, WB
GTX125989	Influenza A virus NP (nucleoprotein)	Rb pAb	ICC/IF, WB
GTX629633	Influenza A virus NP (nucleoprotein)	Ms mAb	ICC/IF, WB
GTX629544	Influenza A virus NP (nucleoprotein)	Ms mAb	WB
GTX28261	Influenza A virus NP (nucleoprotein)	Ms mAb	ELISA, ICC/IF
GTX125990	Influenza A virus NS1 (nonstructural protein)	Rb pAb	ICC/IF, WB
GTX125952	Influenza A virus NS2 (nonstructural protein)	Rb pAb	WB
GTX125953	Influenza A virus NS2 (nonstructural protein)	Rb pAb	WB
GTX125932	Influenza A virus PA protein antibody	Rb pAb	ICC/IF, WB
GTX125933	Influenza A virus PA protein antibody	Rb pAb	ICC/IF, WB
GTX118991	Influenza A virus PA protein antibody	Rb pAb	ICC/IF, WB
GTX125923	Influenza A virus PB1 protein antibody	Rb pAb	ICC/IF, WB
GTX125925	Influenza A virus PB2 protein antibody	Rb pAb	ICC/IF, WB
GTX125926	Influenza A virus PB2 protein antibody	Rb pAb	ICC/IF, WB
GTX125928	Influenza A virus M1 (matrix protein)	Rb pAb	WB
GTX127356	Influenza A virus M1 (matrix protein)	Rb pAb	ELISA, WB
GTX127294	Influenza A virus H1N1 HA (Hemagglutinin)	Rb pAb	WB
GTX127295	Influenza A virus H1N1 HA (Hemagglutinin)	Rb pAb	WB
GTX127357	Influenza A virus H1N1 HA (Hemagglutinin)	Rb pAb	ICC/IF, WB
GTX629750	Influenza A virus H1N1 HA (Hemagglutinin) antibody	Ms mAb	ICC/IF, WB
GTX629746	Influenza A virus H1N1 HA (Hemagglutinin) antibody [GT521]	Ms mAb	WB
GTX125974	Influenza A virus H1N1 NA (Neuraminidase) antibody	Rb pAb	WB
GTX629695	Influenza A virus H1N1 NA (Neuraminidase) antibody [GT172]	Ms mAb	WB
GTX629696	Influenza A virus H1N1 NA (Neuraminidase) antibody [GT288]	Ms mAb	ICC/IF, WB
GTX127363	Influenza A virus H3N2 HA (Hemagglutinin) antibody	Rb pAb	IHC-P, WB
GTX127984	Influenza A virus H5N1 NA (Neuraminidase) antibody	Rb pAb	WB
GTX127302	Influenza A virus H7N7 HA (Hemagglutinin) antibody	Rb pAb	WB
GTX127303	Influenza A virus H7N7 HA (Hemagglutinin) antibody	Rb pAb	WB
GTX127305	Influenza A virus H9N2 HA (Hemagglutinin) antibody	Rb pAb	WB
GTX127306	Influenza A virus H9N2 HA (Hemagglutinin) antibody	Rb pAb	WB
GTX127307	Influenza A virus H9N2 HA (Hemagglutinin) antibody	Rb pAb	WB
GTX127299	Avian Influenza A virus H5N3 HA (Hemagglutinin) antibody	Rb pAb	WB

Product Highlight - Influenza B


Influenza B Virus M antibody (GTX128537)		Influenza B Virus Neuraminidase (NA) antibody (GTX128540)
ICC/IF analysis with Influenza B Virus M antibody on MDCK cells infected with influenza B virus (Taiwan B70555).		ICC/IF analysis with Influenza B Virus Neuraminidase (NA) antibody on MDCK cells infected with influenza B virus (Taiwan B70555).


Influenza B Virus Hemagglutinin (HA) antibody (GTX128542)		Influenza B Virus NP antibody [GT371] (GTX629882)
ICC/IF analysis with Influenza B Virus Hemagglutinin (HA) antibody on MDCK cells infected with influenza B virus (Taiwan B70555).		ICC/IF analysis with Influenza B Virus NP antibody on MDCK cells infected with influenza B virus.


Influenza B Virus M antibody (GTX128536)	Influenza B Virus NP antibody [GT371] (GTX629882)	Influenza B Virus Hemagglutinin (HA) antibody (GTX128542)	Influenza B Virus antibody (GTX128544)
WB analysis with Influenza B Virus M antibody. (A) Non-infection control. (B) Medium harvested from cells infected with Influenza B virus.	WB analysis with Influenza B Virus NP antibody on MDCK cells. (A) Non-infection control. (B) Infection of influenza B virus (Taiwan 70555)	WB analysis with Influenza B Virus Hemagglutinin (HA) antibody. (A) Non-infection control. (B) Medium harvested from cells infected with Influenza B virus.	WB analysis with Influenza B Virus antibody. (A) Non-infection control. (B) Medium harvested from cells infected with Influenza B virus.

Cat. No.	Product Name	Host & Clonality	Application
GTX128544	Influenza B Virus antibody	Rb pAb	WB
GTX128536	Influenza B Virus M antibody	Rb pAb	WB
GTX128537	Influenza B Virus M antibody	Rb pAb	ICC/IF, WB
GTX128540	Influenza B Virus Neuraminidase (NA) antibody	Rb pAb	ICC/IF
GTX128541	Influenza B Virus Neuraminidase (NA) antibody	Rb pAb	ICC/IF
GTX629882	Influenza B Virus NP antibody [GT371]	Ms mAb	ICC/IF, WB
GTX629883	Influenza B Virus NP antibody [GT382]	Ms mAb	ICC/IF, WB
GTX128538	Influenza B Virus NP antibody	Rb pAb	ICC/IF, WB
GTX128539	Influenza B Virus NP antibody	Rb pAb	ICC/IF, WB
GTX128542	Influenza B Virus Hemagglutinin (HA) antibody	Rb pAb	ICC/IF, WB
GTX128543	Influenza B Virus Hemagglutinin (HA) antibody	Rb pAb	ICC/IF, WB

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一种可以防御不同亚型流感病毒的通用疫苗已接近成为现实！

Selected Antibodies for Influenza Virus

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